一、基本信息
明新，四川省高层次留学归国人才，主要研究方向为核酸药物和荧光核苷探针的设计合成，主持完成省部级项目2项，厅局级项目1项，以第一作者或通讯作者发表SCI论文20篇。
二、主持科学研究项目
1.四川省科技厅国际交流与合作项目2013HH0054,碱基和糖修饰的吡咯胞嘧啶类似物的合成和性质研究。
2.教育部留学回国人员科研启动基金，与鸟嘌呤形成额外氢键的吡咯胞嘧啶类似物的合成和性质研究。
3.四川省教育厅，重点项目，14ZA0228，基于叠氮和炔烃环加成反应的核苷修饰和性质研究。
三、主持教学研究项目
1.研究生“课程思政”设计及实施效果研究，校级
四、主要讲授课程
1.硕士研究生：小分子化学药物设计策略
2.本科生课程：有机化学，天然药物化学，药物化学实验
五、主要代表性成果
1.Kuang Shuang, Liu Shuhan, Wang Shiyu, Yang Liang, Zeng Yingchun*,Ming Xin*Folate-receptor-targeted co-self-assembly carrier-free gemcitabine nanoparticles loading indocyanine green for chemo-photothermal therapy. Frontiers in Bioengineering and Biotechnology. 2023, 11, 1266652.
2.Li Jinsi; Fang Xuerong;Ming Xin*. Visibly emitting thiazolyl-uridine analogues as promising fluorescent probes, The Journal of Organic Chemistry, 2020, 85, 4602-4610.
3.MingXin; Frank Seela, A nucleobase discriminating pyrrolo-dC click adduct designed for DNA fluorescence mismatch sensing. Chemistry-A European Journal, 2012, 18, 9590-9600.
4.Yongqi Qiao#, Xuerong Fang#, Shuhan Liu#, Shiyu Wang, Shuang Kuang, Peiwen Li, Yiying Wu*,Xin Ming*. Fluorescent inosine analogues: synthesis, cytotoxicity activity and
self -assembly nanoparticle for live cell image. Tetrahedron 2023, 131, 133230.
5.Fang Xuerong#, Gao Qian#; Zhang Wen; Sun Hongjie,Ming Xin*, Multisensing emissive 8-phenylethynylated 2'-deoxyadenosines and 2'-deoxyisoguanosines. Tetrahedron. 2020, 76,130795.
6.MingXin; Ping Ding; Peter Leonard; Simona Budow; Frank Seela, Parallel-stranded DNA: enhancing duplex stability by the “G-clamp”and a pyrrolo-dC derivative. Organic & Biomolecular Chemistry. 2012, 10, 1861-1869.
7.Xuerong Fang#, Jinsi Li#, Qianqian Zhong,Xin Ming*. Synthesis and cytostatic activity of emissive 7-thiazolyl-7-deazapurine nucleosides. Tetrahedron 2021, 94, 132336。
8.Wen Zhang#, Qian Gao#, Shuxian Wei, Bicheng Fu, Qian Yang,Xin Ming*. Synthesis of 8-substituted 2'-deoxyisoguanosines via unprotected 8-brominated 2-amino-2' -deoxyadenosine.Chemistry & Biodiversity, 2018, 15, e1700335.
9.Xin He#, Shuang Kuang#, Qian Gao, Yuxin Xie,Xin Ming*. Bright fluorescent purine analogues as promising probes. Nucleosides, Nucleotides & Nucleic Acids. 2022, 41, 45-60.
10.Xin Ming, Frank Seela*. Efficient Synthesis of the tRNA Nucleoside PreQ0, 7-Cyano-7-
deazaguanosine, via Microwave-Assisted Iodo→Carbonitrile Exchange. Chemistry & Biodiversity, 2010, 7, 2616-2621.
六、联系方式
E-mail：mingxin@cmc.edu.cn
