一、基本信息
曾迎春,四川大学华西beat365正版唯一官网理学学士、药剂学理学博士,beat365正版唯一官网副教授,研究方向主要为:缓控释及靶向递药系统的研究。主持国家自然科学基金、四川省基金、国家重点实验室开放课题等项目共7项;以第一作者或通讯作者在Acta pharmacologica Sinica、Journal of Materials Chemistry B、Journal of Drug Delivery Science and Technology等期刊公开发表科研论文10余篇。入选学院2024年度登峰计划,获2024年度学院创新人才奖“优秀人才”称号。
二、主持科学研究项目
1. 国家自然科学基金委员会,青年科学基金项目,82104084,针对帕金森病的脑神经元靶向传递体递药系统研究,2022/01/01至2024/12/31,在研,主持。
2.省部共建生物催化与酶工程国家重点实验室,开放课题,SKLBEE20230013,Argonaute核酸酶的靶向递送及其用于肝癌精准治疗的研究,2023/12/31至2025/12/31,在研,主持。
3.四川省科技厅,面上项目,2019YJ0372,针对胰腺癌的吉西他滨与环丙沙星共给药靶向递药系统研究,2019/01/30至2022/01-29,结题,主持。
三、主持教学研究项目
1.成都市校企联合人才培养项目,YXYJG02103,药物制剂技术实训——以片及为例,药学技能实训项目,2024/07-2025/07,在研,主持。
2. 学院校级教改项目,JG2023007,工业药剂学实验课程教学方法与评价体系研究,2023/9-2025/9,在研,主持。
3. 学院校级教改项目,微视频教学在工业药剂学教学中的应用——以片剂为例,一般项目,2020/9-2022/9,结题,主持。
四、主要讲授课程
1. 硕士研究生:《论文写作指导》、《药品质量管理》
2. 本科生课程:《工业药剂学》、《药剂学》
五、主要代表性成果
1.Shuang Kuang, Shuhan Liu, Shiyu Wang, Liang Yang, Yingchun Zeng*, Xin Ming*. Folate-receptor-targeted co-self-assembly carrier-free gemcitabine nanoparticles loading indocyanine green for chemo-photothermal therapy. Frontiers in Bioengineering and Biotechnology. 2023,11:1266652.
2.Linyu Xiao, Bingjie Zhou, Shi Luo, Lang Deng, Yuan Xue, Ling Zhang, Zhengwu Du, Peiwen Li, Li Wang, Bole Tian, Zhirong Zhang*, Yingchun Zeng*. Liposomal co-delivery system encapsulating celastrol and paclitaxel displays highly enhanced efficiency and low toxicity against pancreatic cancer. Journal of Drug Delivery Science and Technology. 2022, 79: 103947.
3.Yue Su#, Huiru Lu#, Qi Li#, Zhouchuan Shao, Shuxiang Wang, Yue Quan, Yingchun Zeng*, Yaxin Zheng*. Driving co-precipitation of hydrophobic drugs in water by conjugating alkyl chains. Journal of Drug Delivery Science and Technology. 2021, 66: 102816.
4.Chunmei Long#, Qi-xue Zheng#, Yi Zhou, Yuanting Liu, Liuping Gong, Yingchun Zeng*, Sha Liu*. N-linoleyltyrosine exerts neuroprotective effects in APP/PS1 transgenic mice via cannabinoid receptor-mediated autophagy. Journal of Pharmacological Sciences. 2021, 147:315-24.
5.Yingchun Zeng*, Yu Ma, Zhengyu Yang, Jiamin Mao, Yaxin Zheng*. Antihyper uricemic efficacy of Scopoletin-loaded Soluplus micelles in yeast extract/potassium oxonate-induced hyperuricemic mice. Drug Development and Industrial Pharmacy. 2020, 46(9): 1150-7.
6.Peiwen Li, Shi Luo, Linyu Xiao, Bole Tian, Li Wang, Zhirong Zhang, Ying chun Zeng*. A novel gemcitabine derivative-loaded liposome with great pancreas-targeting ability. Acta Pharmacologica Sinica. 2019, 40(11): 1448-56.
7.Yaxin Zheng*, Xueling Yan, Yalun Wang, Xing Duan, Xinming Wang, Chaorong Chen, Dongmei Tian, Zhihong Luo, Zhonglin Zhang*, Yingchun Zeng*. Hydrophobized SN38 to redox-hypersensitive nanorods for cancer therapy. Journal of Materials Chemist B. 2018, 7: 265-76.
8.Yingchun Zeng, Sha Li, Chang Liu, Tao Gong, Xun Sun, Yao Fu*, Zhirong Zhang*. Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo. Acta pharmacologica Sinica. 2017, 38(3): 424-33.
9.Yingchun Zeng, Sha Li, Chang Liu, Tao Gong, Xun Sun, Yao Fu*, Zhirong Zhang*. Validated LC-MS/MS method for the determination of scopoletin in rat plasma and Its application to pharmacokinetic studies. Molecules. 2015, 20(10): 18988-9001.
10. 曾迎春,纪忠华,谢兴亮,张全,郑雅鑫.基于Soluplus的东莨菪内酯胶束在Caco-2细胞上的摄取和代谢[J].中国药学杂志,2018,53(23):2029-2033.
六、联系方式
E-mail:102017018@cmc.edu.cn